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UTHealth Researchers Link PRKG1 Genetic Mutation to Thoracic Aortic Disease

Posted on Wednesday, August 7th, 2013, by with Comments Off

HOUSTON – (Aug. 7, 2013) – A multi-institutional team led by Dianna Milewicz, M.D., Ph.D., of The University of Texas Health Science Center at Houston (UTHealth) has found a recurrent genetic mutation that has been linked to deadly thoracic aortic dissections in family members as young as 17 years of age.

The gene known as PRKG1 makes a protein called cGMP-dependent kinase, type I. The PRKG1 mutation alters the function of the protein and causes the muscle cells in the wall of the aorta to respond incorrectly to pulsatile blood flow from the heart, and the change in this one protein ultimately causes thoracic aortic aneurysm and acute aortic dissection. The mutation was identified in four families, including three in the United States. The majority of the affected family members suffered acute aortic dissections at young ages (17 to 51 years). (more…)


Team Ritter Mom-Daughter Pair Selling Non-slip Headbands to Raise Money for the John Ritter Foundation

Posted on Tuesday, July 23rd, 2013, by with Comments Off

UPDATE 9/11/13: THE HEADBANDS ARE SOLD OUT! THANK YOU FOR YOUR SUPPORT. Donations to support Beth and Aubrey’s efforts can be made through their Crowdrise fundraising page: http://www.crowdrise.com/TeamRitterINGNYCMarathon2013/fundraiser/aubreypollesch.

Beth Hook and Aubrey Pollesch are a mother and daughter teamed up to run the 2013 ING NYC Marathon on The John Ritter Foundation’s Team Ritter.  They have a great story to tell and are full of innovative ideas for raising funds to reach and exceed their $3,000 fundraising goal.  To support their cause, Beth’s other daughter, Allie, is making non-slip headbands and selling them for donations.  Please read the story Aubrey wrote about why Team Ritter is so important to their family and please consider ordering a headband (or two or four or more):

What if your knowledge could save someone’s life?

My mom and I are honored to be chosen as representatives of Team Ritter!  And, we are honored to use our love and passion for running to raise money for a cause dear to our hearts.  We would love nothing more than to raise further awareness about aortic health.  Why? Because the knowledge we had saved my dad’s life twice.  And, we would love to help save more lives.  (more…)


The John Ritter Foundation Introduces the Team Ritter 2013 ING NYC Marathon Team

Posted on Monday, July 22nd, 2013, by with Comments Off

The John Ritter Foundation (JRF) is proud to have been selected as an official charity of the ING New York City Marathon for the second year in a row.  The marathon traditionally takes place on the first Sunday in November and this year will be held on Sunday, November 3, 2013.  This is an amazing opportunity to increase awareness of thoracic aortic disease, as well as raise funds to support education and research.

Funds from the NYC Marathon raised for the JRF will go to the John Ritter Research Program in Aortic and Vascular Diseases (JRRP) at The University of Texas Health Science Center at Houston (UTHealth) to identify genes or altered DNA that increases someone’s risk for an acute aortic dissection.  The funds will also be used to provide support, information, and resources to individuals diagnosed with thoracic aortic aneurysms/dissections and their families and for aortic disease awareness and education activities.

The team is very enthusiastic and motivated to help the JRF and JRRP in our work together to prevent deaths due to acute aortic dissection.  Please read their stories and show your support by making a donation to one or more of the runners by visiting Edward Norton’s Crowdrise online fundraising community:  http://www.crowdrise.com/TeamRitterINGNYCMarathon2013.

 

 

http://www.ingnycmarathon.org/   http://www.nyrr.org/

Aortic Disease Support Group Meeting Scheduled in Ann Arbor, Michigan on July 22, 2013

Posted on Thursday, June 6th, 2013, by with Comments Off

It can be difficult to find others to talk to who understand what aortic disease is like.  The John Ritter Research Program is pleased to pass along information about a support group meeting organized by a survivor of aortic dissection in Michigan.  Everyone that has been affected by aortic disease is welcome to attend and support each other.  Here are the details: (more…)


Survivors of Aortic Dissection Support Group Meeting Scheduled in Ridgewood, New Jersey, on June 11, 2013

Posted on Wednesday, June 5th, 2013, by with Comments Off

It can be difficult to find others to talk to who understand what an aortic dissection survivor has been through.  The John Ritter Research Program is pleased to pass along information about a group meeting that a Nurse Practitioner has organized in New Jersey.  Here are the details:

A support group meeting for survivors of aortic dissection is scheduled to take place in in Ridgewood, NJ at The Valley Hospital on Tuesday, June 11 from 5:30 – 7:00 p.m. Eastern time.

For more information or to see how you can be involved, please contact Andrea Storper, NP, at 201-447-8418 or storan@valleyhealth.com.


A Yummy Way to Help Raise Funds for the John Ritter Foundation

Posted on Wednesday, June 5th, 2013, by with Comments Off

Now you can make and eat tantalizing treats and raise money to support the John Ritter Foundation (JRF) all at the same time! (more…)


John Ritter Foundation Selected to Be a Charity Partner of the 2013 ING NYC Marathon

Posted on Monday, April 22nd, 2013, by with Comments Off

The John Ritter Foundation (JRF) announced it was selected as an official charity of the ING New York City Marathon to take place on Sunday, November 3, 2013.  What a great opportunity to increase awareness of thoracic aortic disease, as well as raise funds to support education and research!

JRF is currently recruiting runners to join Team Ritter.  For more information or to sponsor the team, please read the announcement on the JRF website.

If you are not a runner but would like to support Team Ritter, click here.  Donations to JRF can also be made through the JRF website.

Congratulations, John Ritter Foundation!!


Research on Bicuspid Aortic Valves at the University of Texas Health Science Center at Houston

Posted on Friday, April 12th, 2013, by with Comments Off

Research on the genetics of bicuspid aortic valves (BAVs) is underway at the John Ritter Research Program in Aortic and Vascular Diseases at the University of Texas Health Science Center at Houston (UTHealth).  Led by Dr. Siddharth Prakash, the research team aims to determine the mechanisms and cardiac complications of BAV disease.

If you have questions or are interested in participating, more information is available here or by contacting the Study Coordinator, Josephine Turner (Josephine.A.Turner@uth.tmc.edu).  Patients can refer themselves for the study; it is not necessary to be referred by a physician.


Paint & Sip for a Cause on April 13, 2013 in Saratoga Springs, NY

Posted on Saturday, April 6th, 2013, by with Comments Off

This is your chance to paint your own masterpiece and raise money to support efforts to increase awareness and genetic research on thoracic aortic aneurysms and dissections.  How cool is that?

This event will honor the memory of Cliff Klein and the positive impact he had on many people’s lives.  We thank Sarah Jurica for organizing this and for her support of the John Ritter Foundation.

Date:  Saturday, April 13, 2013

Time:  4:00 p.m. to 6:00 p.m.

Location:  Saratoga Paint & Sip Studio, 80 Henry Street, Saratoga Springs, NY  12866

Click here to register:  https://www.saratogapaintandsip.com/calendar/john-ritter-foundation-fundraiser/


Survivors of Aortic Dissection Group Meeting Scheduled in Ann Arbor, Michigan on April 22, 2013

Posted on Friday, April 5th, 2013, by with Comments Off

It can be difficult to find others to talk to who understand what an aortic dissection survivor has been through.  The John Ritter Research Program is pleased to pass along this information about a group meeting that one survivor has organized in Michigan.  Here are the details:

Chris Kasper (chriskasper17@gmail.com) has organized a support and informational group meeting for survivors of aortic dissection, their families, and their caregivers to take place in Ann Arbor, Michigan on Monday, April 22, 2013, from 10:00 a.m. to 12:00 p.m. Eastern time.  The meeting will be held at:

University of Michigan

EAA Health & Geriatrics Center

Room B1-407

4260 Plymouth Rd.

Ann Arbor, MI 48109

There are three buildings which make up this “campus”.  The building where the meeting will be held is the one in the center.  When you enter the building, take the elevator to level B1.  Exit straight out of the elevator and go through a set of double doors to the left of Java city.  The conference room is B1-407 and will be on the right side of the hallway across from the patio.  Please contact Chris directly at chriskasper17@gmail.com with any questions.  

A subsequent meeting is being planned for July 22, 2013 in the same location.  Chris is hoping to make this a quarterly event.

Thank you, Chris, for sharing this information with us and for providing survivors with an opportunity to meet and talk!


 


 

 

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